Glutathione Liquid Spray

Glutathione is the body's own three-amino-acid antioxidant. Intranasal glutathione is one of the few spray forms in the catalog with real human research, mostly from small Parkinson's disease studies.

Glutathione neutralizes reactive oxygen species inside cells. In a small brain-imaging study, intranasal glutathione raised glutathione levels in a deep brain region for about an hour.

In 15 people with Parkinson's, a single intranasal dose raised measured brain glutathione to roughly 2.4–2.7 times baseline at 45 minutes, without a placebo arm. A 3-month randomized trial found no difference in adverse events versus placebo, and a 12-week phase IIb trial found it no better than placebo for symptoms. The studies used compounded solutions of a different strength, and the solution lost potency over weeks of refrigerated storage.

Nasal trials reported sinus irritation and headache (also on placebo), under-eye puffiness, and one case of heart muscle disease with unclear cause. Glutathione degrades in solution, and a multi-dose water-based bottle needs preservative or sterility control that the catalog does not disclose.

No FDA-approved glutathione drug. Glutathione is in FDA 503A Category 1 (under evaluation), so licensed pharmacies may compound it with a prescription under FDA's interim policy; this research product is not a compounded medicine. Not prohibited by WADA as a substance in 2026.