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Dissolving StripsCOGNITIVE & NEURO
Evidence grade D

Melts Pro Selank + Semax Dissolving Strips

The combination has never been studied, so it is graded D. Neither peptide has human or animal data as a mouth-dissolving strip; each alone is graded C, based on small Russian nasal studies.

Strengths
20 strips (one line says 30); lot labeled "5 mg / 5 mg"
Also known as
Melts Pro Selank/Semax strips
Contains
Selank, Semax
Molecule
Two 7-amino-acid peptides in a dissolving film

Origin

A mouth-dissolving film containing Selank and Semax, two peptides approved only in Russia, and only as nasal drops.

How it works

The strip contains the same two neuropeptides as the catalog's Selank and Semax vials: Selank, a stabilized tuftsin analog, and Semax, a modified ACTH fragment. Both have been studied for effects on the nervous system when given intranasally. Whether either is absorbed from a mouth strip is unknown.

What the research shows

No study of Selank and Semax given together was found, and no published data exist for either peptide by sublingual or buccal route; all labeling and human data are intranasal. Peptides in the mouth face salivary enzymes and loss by swallowing. For comparison, approved under-the-tongue or oral peptide drugs absorb poorly: sublingual desmopressin, a similar-size peptide, has about 0.25% bioavailability, and oral semaglutide about 0.4–2% even with an absorption enhancer. No enhancer is disclosed for this strip.

Key studies

  • Nocdurna (desmopressin) prescribing information Sublingual 9-amino-acid peptide drug with 0.25% absolute bioavailability, a benchmark for mouth absorption of small peptides.
  • Rybelsus (oral semaglutide) prescribing information Even with the enhancer SNAC, oral bioavailability is about 0.4–2%.

Safety findings

Component cautions apply; Semax's Russian label lists anxiety disorders and seizure history as contraindications, while Selank is marketed for anxiety, so the pairing mixes opposing label positions. Mouth irritation and reactions to undisclosed excipients are unstudied, and the unclear strength means exposure cannot be known. Neither component has data in pregnancy, breastfeeding or under 18.

Regulatory status

Neither peptide is FDA-approved. Selank's compounding nomination was withdrawn; Semax received an 8–5–1 FDA advisory committee vote in July 2026 recommending 503A bulks listing, but the vote is advisory and no final rule had followed as of October 2026, so neither is compoundable. Neither is named on the 2026 WADA list, and both are approved in Russia.

Catalog notes

Current lot SEMSEL5-0803 has a certificate (99.76% purity, COA7604, August 17, 2026). The label reads '5 mg / 5 mg' without saying whether that is per strip or per pack, and the strip count is listed as both 20 and 30. Storage is listed as refrigerated, while the SDS lists −20 °C.